Is it possible to run UBOS Mesh on an operating system other than UBOS Linux?

/docs/developers/faq/mesh-on-different-os/

Yes. There is nothing in UBOS Personal Data Mesh that depends on facilities that only exist on UBOS Linux.

We currently do not provide any packages or other support, however, and building those may not be worth your while: if your host operating system is something else, why not run UBOS Personal Data Mesh in UBOS Linux container? That might be easiest.